Background: Inflammatory pseudotumor (IP) is a collection of histocytes, and inflammatory cells including plasma cells, lymphocytes, eosinophils, and fibroblasts. The IP in the nasopharyngeal space is exceedingly rare. If left untreated it may cause permanent and serious complications.
Case presentation: A 46-year-old man with left nasal congestion, and a hearing decrement in his left ear was admitted to Loghman-hakim Hospital. In audiometric evaluations, there was a 20 decibels gap in the hearing threshold between two ears. In nasopharyngoscopy, there was a large gray-to-white mass with intact epithelia in the nasopharynx. In a computed tomography scan, a large soft mass in the left nasopharynx, with no evidence of bone destruction. Magnetic resonance imaging (MRI) homogenous isointense and hypointense mass in T1-weighted and T2-weighted images, respectively. Based on all the investigations, the risk of malignancy was considered low. As a result, the final diagnosis of IP was considered for him.
Discussion: IP can occur anywhere in the body and encompasses a diverse range of masses, including inflammatory myofibroblastic tumors, IPTs of lymph nodes, orbit, and spleen, genitourinary pseudosarcomatous, and post-infectious or reparative disorders. The tumors usually affect children and young adults, and the precise incidence and prevalence of IPs are difficult to estimate. The main treatment is surgical resection, corticosteroids, or both, with alternative treatments including small molecule inhibitors, immunoglobulin, and radiotherapy.
Conclusion: Sinonasal IPs are exceedingly rare. In this article, we reported a mid-aged man with an IP in his left nasopharynx space.